Combining plant growth-promoting rhizobacteria (PGPR) and nanoparticles (NPs) offers a promising strategy for enhancing soil quality and crop yields under adverse conditions. This review highlights how PGPR and NPs interact to improve soil texture, balance nutrients, and boost agricultural productivity. Research suggests that their combined application can significantly surpass the benefits of each individually, pointing to their potential for large-scale agricultural advancements in sustainable food security.